I think your question might be too broad... Unlike density matrices which are positive semidefinite operators, the Wigner function in phase space is not. (Conversely, a classical positive definite phase space Liouville density Wigner transforms to a non-positive definite "Groenewold operator", Bracken and Wood.)
You might consider, if you already haven't, the Husimi distribution, which, being a Weierstrass transform of the Wigner function, corresponds to low-pass filtering thereof,
and is, in fact, positive semidefinite---the price paid for loss of information, aggressively non-unitary to be sure, due to this Gaussian blurring.
But it might help if your question were narrower and more specific.
This post imported from StackExchange Physics at 2016-03-28 19:42 (UTC), posted by SE-user Cosmas Zachos